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Article

Implication of genetic variants in primary microRNA processing sites in the risk of multiple sclerosis.

EBioMedicine - 1 Jun 2022

Hecker Michael, Fitzner Brit, Putscher Elena, Schwartz Margit, Winkelmann Alexander, Meister Stefanie, Dudesek Ales, Koczan Dirk, Lorenz Peter, Boxberger Nina, Zettl Uwe Klaus

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system with a well-established genetic contribution to susceptibility. Over 200 genetic regions have been linked to the inherited risk of developing MS, but the disease-causing variants and their functional effects at the molecular level are still largely unresolved. We hypothesised that MS-associated single-nucleotide...

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Identifiers

PMID: 35561450
DOI: 10.1016/j.ebiom.2022.104052
PMCID: PMC9111935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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