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Article

Characterization of a novel mutation in NS1 protein of influenza A virus induced by a chemical substance for the attenuation of pathogenicity.

PloS one - 1 Jan 2015

Sasaki Kohei, Hayashi Kyoko, Lee Jung-Bum, Kurosaki Fumiya, Hayashi Toshimitsu

Abstract excerpt

It is generally accepted that live attenuated influenza vaccine (LAIV) has the potential for use as a vaccination against flu. In this study, we demonstrated the nature of an influenza A virus (IAV) mutant induced by treating the IAV with a stable furan derivative, (1R,2R)-1-(5'-methylfur-3'-yl)p...

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Identifiers

PMID: 25793397
DOI: 10.1371/journal.pone.0121205
PMCID: PMC4368802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25793397-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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