Article

Potential and action mechanism of favipiravir as an antiviral against Junin virus

2021-12-15

Abstract excerpt

<h4>ABSTRACT</h4> Favipiravir is a nucleoside analogue that inhibits the replication and transcription of a broad spectrum of RNA viruses, including pathogenic arenaviruses. In this study, we isolated a favipiravir-resistant mutant of Junin virus (JUNV), which is the causative agent of Argentine hemorrhagic fever, and analyzed the antiviral mechanism of favipiravir against JUNV. Two amino acid substitutions, N462...

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Identifiers and source

Literature Corpus work: 7283ebe1-611f-5fb4-bd94-2fbf5bca4961
DOI: 10.1101/2021.12.14.472716

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