Article

Antiviral effect of a nucleic acid hydrolyzing scFv against oseltamivir resistant influenza A virus

2021-02-22

Abstract excerpt

Influenza viral genome is frequently mutated due to antigenic shift and drift, and therefore the existing antiviral drugs have been suffered from low efficacy against the viruses. Here we report an innovative strategy for treating influenza Type A (IAV) infection by 3D8 single chain variable fragment (scFv) showing intrinsic viral RNA hydrolyzing activity, cell penetration activity and the epidermal cell penetrati...

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Literature Corpus work: bcc3d6e3-109b-5032-872f-f00e51c3be5c
DOI: 10.1101/2021.02.19.432068

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Antiviral effect of a nucleic acid hydrolyzing scFv against oseltamivir resistant influenza A virusDOI 10.1101/2021.02.19.432068Read

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