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Article

Processing of protein ADP-ribosylation by Nudix hydrolases.

The Biochemical journal - 1 Jun 2015

Palazzo Luca, Thomas Benjamin, Jemth Ann-Sofie, Colby Thomas, Leidecker Orsolya, Feijs Karla L H, Zaja Roko, Loseva Olga, Puigvert Jordi Carreras, Matic Ivan, Helleday Thomas, Ahel Ivan

Abstract excerpt

ADP-ribosylation is a post-translational modification (PTM) of proteins found in organisms from all kingdoms of life which regulates many important biological functions including DNA repair, chromatin structure, unfolded protein response and apoptosis. Several cellular enzymes, such as macrodomain containing proteins PARG [poly(ADP-ribose) glycohydrolase] and TARG1 [terminal ADP-ribose (ADPr) protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Poly(ADP-ribose) Polymerases

Share to Protein Processing, Post-Translational

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Share to Sequence Homology, Amino Acid

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

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Identifiers

PMID: 25789582
DOI: 10.1042/BJ20141554
PMCID: PMC6057610

Genes

PARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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