Article
Contribution of susceptibility variants at FCGR2A and 13q12 to the risk of relapse among Japanese patients with ulcerative colitis.
Journal of gastroenterology - 1 Nov 2015
Asano Kouichi, Esaki Motohiro, Umeno Junji, Hirano Atsushi, Maehata Yuji, Moriyama Tomohiko, Nakamura Shotaro, Matsumoto Takayuki, Kitazono Takanari
Abstract excerpt
BACKGROUND: Recent genome-wide association studies have identified nearly 100 susceptibility genes for ulcerative colitis (UC). However, the contribution of susceptibility variants for UC to clinical outcome has scarcely been reported. The aim of this study was to investigate whether UC-associated genetic variants confer a risk of clinical relapse. METHODS: One hundred and nine consecutive Japanese subjects with...
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