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HLA-DQA1*05 and upstream variants of PPARGC1B are associated with infliximab persistence in Japanese Crohn’s disease patients

2023-04-06

Abstract excerpt

<title>Abstract</title> <p>Recently, the HLA-DQA1*05 (rs2097432) genetic variation has been reported to be linked to early Infliximab (IFX) treatment failure in the Caucasian Crohn’s disease (CD) population, but that evidence is scarce in the Asian population. This study aimed to investigate the relationship between rs2097432 and the cumulative discontinuation-free time of IFX (IFX persistence) in 189 Japanese IF...

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Literature Corpus work
0f19f3de-7e1b-5fc3-ad72-0916c6ddc3bd
DOI
10.21203/rs.3.rs-2760827/v1
Open publication

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HLA-DQA1*05 and upstream variants of PPARGC1B are associated with infliximab persistence in Japanese Crohn’s disease patientsDOI 10.21203/rs.3.rs-2760827/v1
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