Article
Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
Inflammatory bowel diseases - 1 Sept 2013
Asano Kouichi, Matsumoto Takayuki, Umeno Junji, Hirano Atsushi, Esaki Motohiro, Hosono Naoya, Matsui Toshiyuki, Kiyohara Yutaka, Nakamura Yusuke, Kubo Michiaki, Kitazono Takanari
Abstract excerpt
BACKGROUND: Polymorphisms in the Fcγ receptor genes have been implicated in several autoimmune diseases, including ulcerative colitis (UC). However, most of these reports had not taken into account the effect of copy number variation at this region. METHODS: We investigated the combined effect of...
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