Article
Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts.
Disease models & mechanisms - 1 May 2015
Brunke Sascha, Quintin Jessica, Kasper Lydia, Jacobsen Ilse D, Richter Martin E, Hiller Ekkehard, Schwarzmüller Tobias, d'Enfert Christophe, Kuchler Karl, Rupp Steffen, Hube Bernhard, Ferrandon Dominique
Abstract excerpt
Studying infectious diseases requires suitable hosts for experimental in vivo infections. Recent years have seen the advent of many alternatives to murine infection models. However, the use of non-mammalian models is still controversial because it is often unclear how well findings from these systems predict virulence potential in humans or other mammals. Here, we compare the commonly used models, fruit fly and...
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