Article
Pathogenicity of Aspergillus fumigatus mutants assessed in Galleria mellonella matches that in mice.
Medical mycology - 1 Apr 2011
Slater J L, Gregson L, Denning D W, Warn P A
Abstract excerpt
Aspergillus fumigatus is a clinically important fungus with the ability to cause invasive aspergillosis with high mortality rates in immunocompromised patients and chronic pulmonary aspergillosis in immunocompetent individuals. Virulence of mutants has traditionally been assessed using mammalian hosts such as mice and rats and more recently the fruit fly, Drosophila melanogaster, demonstrated the potential to act...
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