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Article

Detection of BRAF mutation in Chinese tumor patients using a highly sensitive antibody immunohistochemistry assay.

Scientific reports - 18 Mar 2015

Qiu Tian, Lu Haizhen, Guo Lei, Huang Wenting, Ling Yun, Shan Ling, Li Wenbin, Ying Jianming, Lv Ning

Abstract excerpt

BRAF mutations can be found in various solid tumors. But accurate and reliable screening for BRAF mutation that is compatible for clinical application is not yet available. In this study, we used an automated immunohistochemistry (IHC) staining coupled with mouse monoclonal anti-BRAF V600E (VE1) primary antibody to screen the BRAF V600E mutation in 779 tumor cases, including 611 colorectal carcinomas (CRC), 127...

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Share to Antibodies, Monoclonal
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Immunohistochemistry

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Share to Proto-Oncogene Proteins B-raf

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Source

Open in PubMed Open full text

Identifiers

PMID: 25784606
DOI: 10.1038/srep09211
PMCID: PMC4363828

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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