Immunohistochemistry as a quick screening method for clinical detection of BRAF(V600E) mutation in melanoma patients.

doi:10.1007/s13277-014-1759-6

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Immunohistochemistry as a quick screening method for clinical detection of BRAF(V600E) mutation in melanoma patients.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2014

Chen Qiongrong, Xia Chunjiao, Deng Yunte, Wang Mingwei, Luo Ping, Wu Changming, Yue Junqiu, Fang Na, Wang Manxiang, Wei Shaozhong

Abstract excerpt

With the increased uses of targeted therapeutics, diagnostic detection of target mutations becomes essential for the effective clinical applications of targeted therapeutics. Currently, there are two types of methods detecting target mutations in clinics: one is based on DNA sequence and the othe...

Topics

Adult
Aged
Animals
Female
Humans
Immunohistochemistry
Male
Melanoma
Mice
Middle Aged
Mutation
Proto-Oncogene Proteins B-raf
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 24563339
DOI: 10.1007/s13277-014-1759-6

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-24563339-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics