Article
IFITM3 Inhibits SARS-CoV-2 Infection and Is Associated with COVID-19 Susceptibility.
Viruses - 18 Nov 2022
Xu Fengwen, Wang Geng, Zhao Fei, Huang Yu, Fan Zhangling, Mei Shan, Xie Yu, Wei Liang, Hu Yamei, Wang Conghui, Cen Shan, Liang Chen, Ren Lili, Guo Fei, Wang Jianwei
Abstract excerpt
SARS-CoV-2 has become a global threat to public health. Infected individuals can be asymptomatic or develop mild to severe symptoms, including pneumonia, respiratory distress, and death. This wide spectrum of clinical presentations of SARS-CoV-2 infection is believed in part due to the polymorphisms of key genetic factors in the population. In this study, we report that the interferon-induced antiviral factor...
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