A novel susceptibility locus for Takayasu arteritis in the IL12B region can be a genetic marker of disease severity.

doi:10.1007/s00380-015-0661-5

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Article

A novel susceptibility locus for Takayasu arteritis in the IL12B region can be a genetic marker of disease severity.

Heart and vessels - 1 Jun 2016

Matsumura Takayoshi, Amiya Eisuke, Tamura Natsuko, Maejima Yasuhiro, Komuro Issei, Isobe Mitsuaki

Abstract excerpt

Takayasu arteritis (TAK) is an acute and chronic vasculitis of unknown etiology. Recently, our group reported that SNP rs6871626 in the IL12B region had significant association with disease susceptibility to TAK. However, association of the SNP with clinical characteristics of TAK has yet to be determined. Therefore, we assessed whether this SNP was associated with TAK disease severity as represented by early...

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PMID: 25783557
DOI: 10.1007/s00380-015-0661-5

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