Article
Single nucleotide polymorphisms of IL12B are associated with Takayasu arteritis in Chinese Han population.
Rheumatology international - 1 Apr 2017
Wen Xiaoting, Chen Si, Li Ping, Li Jing, Wu Ziyan, Li Yuan, Li Liubing, Yuan Hui, Tian Xinping, Zhang Fengchun, Li Yongzhe
Abstract excerpt
Takayasu arteritis (TA) is a rare autoimmune disease of unknown etiology. Genome-wide association studies (GWAS) have demonstrated association between genetic variants of IL12B and IL6 and TA. Since TA has been reported with ethnic heterogeneity, we sought to investigate whether the single-nucleotide-polymorphisms (SNPs) reported in these studies are associated with TA in the Chinese Han population. A...
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