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Article

Angiogenesis related genes in Takayasu Arteritis (TAK): robust association with Tag SNPs of IL-18 and FGF-2 in a South Asian Cohort.

Journal of human genetics - 1 Jan 2024

Danda Debashish, Goel Ruchika, Kabeerdoss Jayakanthan, Sun Celi, Danda Sumita, Lincy Franklin Anisea, Joseph George, Nath Swapan K

Abstract excerpt

We performed genetic association study for genes encoding angiogenic and angiostatic proteins in patients with Takayasu arteritis (TAK). A total of 96 SNPs involving 60 genes were studied. Genotyping was performed in Fluidigm 96.96 Dynamic Array chip. All statistical analysis for SNP evaluation was performed using PLINK software. Initial analyses revealed five SNPs from three genes [IL-18 (encodes...

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Fibroblast Growth Factor 2
Genetic Predisposition to Disease
Interleukin-18
Polymorphism, Single Nucleotide
Takayasu Arteritis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37848720
DOI: 10.1038/s10038-023-01198-2

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