Article
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
Arthritis & rheumatology (Hoboken, N.J.) - 1 May 2015
Renauer Paul A, Saruhan-Direskeneli Guher, Coit Patrick, Adler Adam, Aksu Kenan, Keser Gokhan, Alibaz-Oner Fatma, Aydin Sibel Z, Kamali Sevil, Inanc Murat, Carette Simon, Cuthbertson David, Hoffman Gary S, Akar Servet, Onen Fatos, Akkoc Nurullah, Khalidi Nader A, Koening Curry, Karadag Omer, Kiraz Sedat, Langford Carol A, Maksimowicz-McKinnon Kathleen, McAlear Carol A, Ozbalkan Zeynep, Ates Askin, Karaaslan Yasar, Duzgun Nursen, Monach Paul A, Ozer Huseyin T E, Erken Eren, Ozturk Mehmet A, Yazici Ayten, Cefle Ayse, Onat Ahmet Mesut, Kisacik Bunyamin, Pagnoux Christian, Kasifoglu Timucin, Seyahi Emire, Fresko Izzet, Seo Philip, Sreih Antoine G, Warrington Kenneth J, Ytterberg Steven R, Cobankara Veli, Cunninghame-Graham Deborah S, Vyse Timothy J, Pamuk Omer N, Tunc S Ercan, Dalkilic Ediz, Bicakcigil Muge, Yentur Sibel P, Wren Jonathan D, Merkel Peter A, Direskeneli Haner, Sawalha Amr H
Abstract excerpt
OBJECTIVE: Takayasu arteritis is a rare large vessel vasculitis with incompletely understood etiology. This study was undertaken to perform the first unbiased genome-wide association analysis of Takayasu arteritis. METHODS: Two independent cohorts of patients with Takayasu arteritis from Turkey and North America were included in our study. The Turkish cohort consisted of 559 patients and 489 controls, and the...
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