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Genes linked to schistosome resistance identified in a genome-wide association study of African snail vectors

27 Jul 2025

Abstract excerpt

Schistosomiasis, a neglected tropical disease, is transmitted by freshwater snails. Interruption of transmission will require novel vector-focused interventions. We performed a genome-wide association study of African snails, Biomphalaria sudanica, exposed to Schistosoma mansoni in an endemic area of high transmission in Kenya. Two snail genomic regions, SudRes1 and SudRes2, were significantly associated with...

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PMID: 40715059
DOI: 10.1038/s41467-025-61760-8

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