Article
Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection.
Scientific reports - 16 Feb 2016
Crellen Thomas, Allan Fiona, David Sophia, Durrant Caroline, Huckvale Thomas, Holroyd Nancy, Emery Aidan M, Rollinson David, Aanensen David M, Berriman Matthew, Webster Joanne P, Cotton James A
Abstract excerpt
Schistosoma mansoni is a parasitic fluke that infects millions of people in the developing world. This study presents the first application of population genomics to S. mansoni based on high-coverage resequencing data from 10 global isolates and an isolate of the closely-related Schistosoma rodhaini, which infects rodents. Using population genetic tests, we document genes under directional and balancing selection...
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