Article
Characterizing genetic variation on the Z chromosome in Schistosoma japonicum reveals host-parasite co-evolution.
Parasites & vectors - 8 May 2024
Zhou An, Zhang Wei, Ge Xueling, Liu Qi, Luo Fang, Xu Shuhua, Hu Wei, Lu Yan
Abstract excerpt
BACKGROUND: Schistosomiasis is a neglected tropical disease that afflicts millions of people worldwide; it is caused by Schistosoma, the only dioecious flukes with ZW systems. Schistosoma japonicum is endemic to Asia; the Z chromosome of S. japonicum comprises one-quarter of the entire genome. Detection of positive selection using resequencing data to understand adaptive evolution has been applied to a variety of...
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