Article
A chromosome-level genome of the human blood fluke Schistosoma japonicum identifies the genomic basis of host-switching
1 Apr 2022
Abstract excerpt
The evolution and adaptation of S. japonicum, a zoonotic parasite that causes human schistosomiasis, remain unclear because of the lack of whole-genome data. We construct a chromosome-level S. japonicum genome and analyze it together with 72 samples representing six populations of the entire endemic region. We observe a Taiwan zoophilic lineage splitting from zoonotic populations ∼45,000 years ago, consistent...