Article
Mouse models of myelin diseases.
Brain pathology (Zurich, Switzerland) - 1 Oct 1998
Werner H, Jung M, Klugmann M, Sereda M, Griffiths I R, Nave K A
Abstract excerpt
Dys- and demyelination are the common endpoints of several inherited diseases of glial cells, which elaborate myelin and which maintain the myelin sheath very much like an "external" cellular organelle. Whereas some of the genes that are affected by mutations appear to be glial-specific, other genes are expressed in many cell types but their defect is restricted to oligodendrocytes or Schwann cells. Many of the...
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