Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sensitive and Noninvasive Detection of Aberrant SFRP2 and MGMT-B Methylation in Iranian Patients with Colon Polyps.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016

Naini M Alizade, Mokarram P, Kavousipour S, Zare N, Atapour A, Zarin1 M Hassan, Mehrabani G, Borji M

Abstract excerpt

BACKGROUND: The pathogenesis of sporadic colorectal cancer (CRC) is influenced by the patient genetic background and environmental factors. Based on prior understanding, these are classified in two major pathways of genetic instability. Microsatellite instability (MSI) and CPG island methylator phenotype (CIMP) are categorized as features of the hypermethylated prototype, and chromosomal instability (CIN) is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colon
Share to Colonic Polyps

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Modification Methylases

Share to DNA Repair Enzymes

Share to Microsatellite Instability

Share to Neoplasm Staging

Share to Precancerous Conditions

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 27221916
DOI: 10.7314/apjcp.2016.17.4.2185

Genes

MGMT
SFRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sensitive and Noninvasive Detection of Aberrant SFRP2 and MGMT-B Methylation in Iranian Patients with Colon Polyps.PMID 27221916Read ↗

Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesionsSemantic proximity Read ↗

Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screeningSemantic proximity Read ↗

Comprehensive DNA Methylation and Mutation Analyses Reveal a Methylation Signature in Colorectal Sessile Serrated Adenomas.Semantic proximity Read ↗

Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2 , and PRIMA1 in plasma samplesSemantic proximity Read ↗

Methylation of SFRP2 gene as a promising noninvasive biomarker using feces in colorectal cancer diagnosis: a systematic meta-analysisSemantic proximity Read ↗

Hypermethylation of SFRP2 as a Potential Marker for Stool-Based Detection of Colorectal Cancer and Precancerous LesionsSemantic proximity Read ↗

MGMT-B gene promoter hypermethylation in patients with inflammatory bowel disease - a novel finding.Semantic proximity Read ↗

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicineSemantic proximity Read ↗

Serrated Colorectal Lesions: An Up-to-Date Review from Histological Pattern to Molecular Pathogenesis.Semantic proximity Read ↗

Molecular characteristics of colorectal serrated polyps and hyperplastic polyps: A STROBE compliant article.Semantic proximity Read ↗

The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.Semantic proximity Read ↗

Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.