Article
Genotype-specific differences in structural features of hepatitis C virus (HCV) p7 membrane protein.
Biochimica et biophysica acta - 1 Jun 2015
Kalita Monoj Mon, Griffin Stephen, Chou James J, Fischer Wolfgang B
Abstract excerpt
The 63 amino acid polytopic membrane protein, p7, encoded by hepatitis C virus (HCV) is involved in the modulation of electrochemical gradients across membranes within infected cells. Structural information relating to p7 from multiple genotypes has been generated in silico (e.g. genotype (GT) 1a), as well as obtained from experiments in form of monomeric and hexameric structures (GTs 1b and 5a, respectively)....
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