Article
Contribution of charged and polar residues for the formation of the E1-E2 heterodimer from Hepatitis C Virus.
Journal of molecular modeling - 1 Oct 2010
Jusoh Siti Azma, Welsch Christoph, Siu Shirley W I, Böckmann Rainer A, Helms Volkhard
Abstract excerpt
The transmembrane domains of the envelope glycoprotein E1 and E2 have crucial multifunctional roles in the biogenesis of hepatitis C virus. We have performed molecular dynamics simulations to investigate a structural model of the transmembrane segments of the E1-E2 heterodimer. The simulations su...
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