Article
Are genetic variants for tobacco smoking associated with cannabis involvement?
Drug and alcohol dependence - 1 May 2015
Agrawal Arpana, Lynskey Michael T, Kapoor Manav, Bucholz Kathleen K, Edenberg Howard J, Schuckit Marc, Brooks Andrew, Hesselbrock Victor, Kramer John, Saccone Nancy, Tischfield Jay, Bierut Laura J
Abstract excerpt
BACKGROUND: Cannabis users are highly likely to also be tobacco cigarette smokers and a proportion of this comorbidity is attributable to shared genetic influences. Three large meta-analyses of genomewide association studies (GWAS) of tobacco smoking have identified multiple genomewide significant (p<5×10(-8)) single nucleotide polymorphisms (SNPs). We examine whether these SNPs are associated with tobacco...
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