Non-POU Domain-Containing Octamer-Binding Protein Negatively Regulates HIV-1 Infection in CD4 + T Cells

Abstract excerpt

HIV-1 interacts with numerous cellular proteins during viral replication. Identifying such host proteins and characterizing their roles in HIV-1 infection can deepen our understanding of the dynamic interplay between host and pathogen. We previously identified non-POU domain-containing octamer-binding protein (NonO or p54nrb) as one of host factors associated with catalytically active preintegration complexes...

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