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Article

Phenotype Switching in Melanoma: Implications for Progression and Therapy

13 Feb 2015

Abstract excerpt

Epithelial-mesenchymal transition (EMT) is a key process associated with the progression of epithelial cancers to metastatic disease. In melanoma, a similar process of phenotype switching has been reported and EMT-related genes have been implicated in promotion to a metastatic state. This review examines recent research on the role of signaling pathways and transcription factors regulating EMT-like processes in...

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Identifiers

PMID: 25763355
DOI: 10.3389/fonc.2015.00031

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