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Article

Expression of Human Endogenous Retrovirus K in Melanomas and Melanoma Cell Lines

15 May 2005

Abstract excerpt

The human endogenous retrovirus K family (HERV-K) comprises 30 to 50 closely related proviruses, most of which are defective. In contrast to all other human endogenous retroviruses, some HERV-K proviruses have maintained open reading frames for all viral proteins. In addition to the structural proteins Gag and Env and the reverse transcriptase, two regulatory proteins (Rec and Np9) have been described. Malignant...

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PMID: 15899808
DOI: 10.1158/0008-5472.can-04-2983

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