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Article

Enrichment of committed human nucleus pulposus cells expressing chondroitin sulfate proteoglycans under alginate encapsulation.

Osteoarthritis and cartilage - 1 Jul 2015

Sun Y, Lv M, Zhou L, Tam V, Lv F, Chan D, Wang H, Zheng Z, Cheung K M C, Leung V Y L

Abstract excerpt

OBJECTIVE: Intervertebral disc (IVD) degeneration is associated with a malfunction of the nucleus pulposus (NP). Alginate culturing provides a favorable microenvironment for the phenotypic maintenance of chondrocyte-like NP cells. However, NP cells are recently evidenced to present heterogeneous populations, including progenitors, fibroblastic cells and primitive NP cells. The aim of this study is to profile the...

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Source

Identifiers

PMID: 25749011
DOI: 10.1016/j.joca.2015.02.166

Genes

IVD
KRT19
CDH2
KRT18
MIA
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Enrichment of committed human nucleus pulposus cells expressing chondroitin sulfate proteoglycans under alginate encapsulation.PMID 25749011Read ↗

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