Article
Genes and childhood leukemia.
Postepy higieny i medycyny doswiadczalnej (Online) - 5 Mar 2015
Kęsy Julita, Januszkiewicz-Lewandowska Danuta
Abstract excerpt
Leukemia is a heterogeneous hematologic malignancy originating from a multipotent hematopoietic stem cell. It ranks among the commonest cancers in childhood and is characterized by excessive proliferation and differentiation block. The process of leukemogenesis is governed by genetic changes at both the cytogenetic and molecular level. According to numerous analyses, a large spectrum of mutations and...
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