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Article

Arc is a flexible modular protein capable of reversible self-oligomerization.

The Biochemical journal - 15 May 2015

Myrum Craig, Baumann Anne, Bustad Helene J, Flydal Marte Innselset, Mariaule Vincent, Alvira Sara, Cuéllar Jorge, Haavik Jan, Soulé Jonathan, Valpuesta José Maria, Márquez José Antonio, Martinez Aurora, Bramham Clive R

Abstract excerpt

The immediate early gene product Arc (activity-regulated cytoskeleton-associated protein) is posited as a master regulator of long-term synaptic plasticity and memory. However, the physicochemical and structural properties of Arc have not been elucidated. In the present study, we expressed and purified recombinant human Arc (hArc) and performed the first biochemical and biophysical analysis of hArc's structure...

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Identifiers

PMID: 25748042
DOI: 10.1042/BJ20141446
PMCID: PMC4422259

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AFM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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