Article
Polymorphisms of nucleotide-binding oligomerization domain 2 (NOD2) gene in miniature dachshunds with inflammatory colorectal polyps.
Veterinary immunology and immunopathology - 15 Apr 2015
Igarashi Hirotaka, Ohno Koichi, Uchida Eri, Fujiwara-Igarashi Aki, Kanemoto Hideyuki, Fukushima Kenjiro, Uchida Kazuyuki, Tsujimoto Hajime
Abstract excerpt
Inflammatory colorectal polyps (ICRPs) frequently occur in miniature dachshunds (MDs) in Japan, typically form multiple polyps with severe neutrophil infiltration. ICRPs are speculated as a novel, breed-specific canine inflammatory bowel disease. Pattern recognition receptors (PRRs) play an important role in the differentiation of pathogens from commensal bacteria and food antigens, and polymorphisms of various...
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