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Article

Functional analysis of pattern recognition receptors in miniature dachshunds with inflammatory colorectal polyps.

The Journal of veterinary medical science - 1 Apr 2015

Igarashi Hirotaka, Ohno Koichi, Fujiwara-Igarashi Aki, Kanemoto Hideyuki, Fukushima Kenjiro, Goto-Koshino Yuko, Uchida Kazuyuki, Tsujimoto Hajime

Abstract excerpt

Inflammatory colorectal polyps (ICRPs) frequently occur in miniature dachshunds (MDs) in Japan. MDs with ICRPs develop multiple polyps with severe neutrophil infiltration that respond to immunosuppressive therapy. Therefore, ICRPs are thought to constitute a novel, breed-specific form of canine inflammatory bowel disease (IBD). Pattern recognition receptors (PRRs) play a key role in the distinction of pathogens...

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Source

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Identifiers

PMID: 25650150
DOI: 10.1292/jvms.14-0505
PMCID: PMC4427745

Genes

TLR2
NOD2
TLR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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