Article
Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease.
Tissue antigens - 1 Aug 2011
Kathrani A, House A, Catchpole B, Murphy A, Werling D, Allenspach K
Abstract excerpt
Inflammatory bowel disease (IBD) is thought to be the most common cause of vomiting and diarrhoea in dogs. Although IBD can occur in any canine breed, certain breeds are more susceptible. We have previously shown that polymorphisms in the TLR4 and TLR5 (toll-like receptor) genes are significantly associated with IBD in German Shepherd dogs (GSDs). In order to allow for the development of novel diagnostics and...
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