A miRNA-binding site single nucleotide polymorphism in the 3'-UTR region of the NOD2 gene is associated with colorectal cancer.

doi:10.1007/s12032-014-0173-7

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Article

A miRNA-binding site single nucleotide polymorphism in the 3'-UTR region of the NOD2 gene is associated with colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Sept 2014

Ahangari Fatemeh, Salehi Rasoul, Salehi Mansour, Khanahmad Hosein

Abstract excerpt

Colorectal cancer (CRC) is one of the common malignancies worldwide. Single nucleotide polymorphisms in miRNA-binding site on gene transcripts are reported to play important role in increased risk of CRC in different population. We performed a case-control study using 88 CRC patients and 88 non-cancer counterparts to evaluate the association between NOD2 rs3135500 polymorphism located at 3' untranslated region of...

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PMID: 25148897
DOI: 10.1007/s12032-014-0173-7

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NOD2

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