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Article

Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro.

PloS one - 1 Jan 2015

Puig Kendra L, Manocha Gunjan D, Combs Colin K

Abstract excerpt

BACKGROUND: Although APP and its proteolytic metabolites have been well examined in the central nervous system, there remains limited information of their functions outside of the brain. For example, amyloid precursor protein (APP) and amyloid beta (Aβ) immunoreactivity have both been demonstrated in intestinal epithelial cells. Based upon the critical role of these cells in absorption and secretion, we sought to...

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Source

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Identifiers

PMID: 25742317
DOI: 10.1371/journal.pone.0119534
PMCID: PMC4351204

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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