Article
Mutation detection of E6 and LCR genes from HPV 16 associated with carcinogenesis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Mosmann Jessica P, Monetti Marina S, Frutos Maria C, Kiguen Ana X, Venezuela Raul F, Cuffini Cecilia G
Abstract excerpt
Human papillomavirus (HPV) is responsible for one of the most frequent sexually transmitted infections. The first phylogenetic analysis was based on a LCR region fragment. Nowadays, 4 variants are known: African (Af-1, Af-2), Asian-American (AA) and European (E). However the existence of sub-lineages of the European variant havs been proposed, specific mutations in the E6 and LCR sequences being possibly related...
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