Article
Analysis of mutations in the E6 oncogene of human papillomavirus 16 in cervical cancer isolates from Moroccan women.
BMC infectious diseases - 16 Aug 2013
Qmichou Zineb, Khyatti Meriem, Berraho Mohamed, Ennaji My Mustapha, Benbacer Laila, Nejjari Chakib, Benjaafar Noureddine, Benider Abdellatif, Attaleb Mohammed, El Mzibri Mohammed
Abstract excerpt
BACKGROUND: Worldwide, cervical cancer is the second most common cancer in women. High-risk human papillomavirus (HPV) play a crucial role in the etiology of cervical cancer and the most prevalent genotype is HPV16. HPV 16 intratypic variants have been reported to differ in their prevalence, biological and biochemical properties. The present study was designed to analyze and identify HPV type 16 E6 variants among...
Topics
- Adult
- Age Factors
- Female
- Genotype
- Human papillomavirus 16
- Humans
- Middle Aged
- Morocco
- Mutation
- Neoplasm Staging
- Oncogene Proteins, Viral
- Repressor Proteins
- Uterine Cervical Neoplasms