Article
Molecular variants of human papillomavirus type 16 and 18 and risk for cervical neoplasia in Portugal.
Journal of medical virology - 1 Dec 2007
Pista Angela, Oliveira Ana, Barateiro Andreia, Costa Helena, Verdasca Nuno, Paixão Maria Teresa
Abstract excerpt
Persistent high-risk human papillomavirus (HPV) infection is considered as the central cause of invasive cervical cancer. Specific HPV 16 and 18 sequence variations were associated with an increased risk for progression. The purpose of this study was to analyze intratypic variations of HPV 16 and 18 within the E6 gene, MY09/11 and LCR regions, and to evaluate the risk of these variants for cervical neoplasia...
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