Article
High grade cervical lesions are caused preferentially by non-European variants of HPVs 16 and 18.
International journal of cancer - 15 Apr 2007
Sichero Laura, Ferreira Silvaneide, Trottier Helen, Duarte-Franco Eliane, Ferenczy Alex, Franco Eduardo Luis, Villa Luisa Lina
Abstract excerpt
The intratypic variability of HPVs 16 and 18 has been extensively studied and has been used as an important tool in epidemiological studies of viral transmission, persistence and progression to clinically relevant cervical lesions. Infections by non-European variants of HPVs 16 and 18 are associated with an increased risk for the development of high grade squamous intraepithelial lesions (HSIL). Our aim was to...
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