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Article

The influence of mitochondrial dynamics on mitochondrial genome stability.

Current genetics - 1 Feb 2018

Prevost Christopher T, Peris Nicole, Seger Christina, Pedeville Deanna R, Wershing Kathryn, Sia Elaine A, Sia Rey A L

Abstract excerpt

Mitochondria are dynamic organelles that fuse and divide. These changes alter the number and distribution of mitochondrial structures throughout the cell in response to developmental and metabolic cues. We have demonstrated that mitochondrial fission is essential to the maintenance of mitochondrial DNA (mtDNA) under changing metabolic conditions in wild-type Saccharomyces cerevisiae. While increased loss of mtDNA...

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PMID: 28573336
DOI: 10.1007/s00294-017-0717-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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