ENU mutagenesis in the mouse.

Abstract excerpt

This article describes the treatment of laboratory mice with the mutagen N-ethyl-N-nitrosourea (ENU) to induce very highly increased rates of mutation throughout the genome. Further, it describes several popular mating schemes designed to produce animals displaying phenotypes associated with the induced mutations.

Topics

• Animals
• Ethylnitrosourea
• Genome
• Humans
• Mice
• Models, Animal
• Mutagenesis
• Mutagens
• Phenotype