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Article

Curcumin restores mitochondrial functions and decreases lipid peroxidation in liver and kidneys of diabetic db/db mice.

Biological research - 22 Dec 2014

Soto-Urquieta María G, López-Briones Sergio, Pérez-Vázquez Victoriano, Saavedra-Molina Alfredo, González-Hernández Gloria A, Ramírez-Emiliano Joel

Abstract excerpt

BACKGROUND: Nitrosative and oxidative stress play a key role in obesity and diabetes-related mitochondrial dysfunction. The objective was to investigate the effect of curcumin treatment on state 3 and 4 oxygen consumption, nitric oxide (NO) synthesis, ATPase activity and lipid oxidation in mitochondria isolated from liver and kidneys of diabetic db/db mice. RESULTS: Hyperglycaemia increased oxygen consumption and...

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Identifiers

PMID: 25723052
DOI: 10.1186/0717-6287-47-74
PMCID: PMC4289591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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