Article
Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy.
Diabetologia - 1 Apr 2001
Hounsom L, Corder R, Patel J, Tomlinson D R
Abstract excerpt
AIMS/HYPOTHESIS: This study compared the effects of streptozotocin-induced diabetes in rats with those of two pro-oxidant interventions; a diet deficient in vitamin E and treatment with primaquine. METHODS: Measurements were made by the classic motor and sensory conduction velocity deficits and by indicators of the breakdown of small fibre phenotype i.e., sciatic nerve content of nerve growth factor and the...
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