Article
Pancreas beta-cells morphology, liver antioxidant enzymes and liver oxidative parameters in alloxan-resistant and alloxan-susceptible Wistar rats: a viable model system for the study of concepts into reactive oxygen species.
Fundamental & clinical pharmacology - 1 Dec 2008
Behr Guilherme Antônio, da Silva Evandro Gomes, Ferreira Amâncio Romanelli, Cerski Carlos Thadeu Schmidt, Dal-Pizzol Felipe, Moreira José Cláudio Fonseca
Abstract excerpt
The aim of this study was to investigate biochemical and antioxidant parameters in alloxan-resistant (ALR) and alloxan-susceptible (ALS) rats. Diabetes was induced in 60-day-old male Wistar rats by a single intraperitonial injection of alloxan (AL, 150 mg/kg). Ten days after induction, a group of rats showed a significant decrease in glycemia. This group was named alloxan-resistant group. Susceptible rats showed...
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