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AR C-106T gene polymorphism and diabetic nephropathy in the Eastern Asians with T2DM: A meta-analysis including 2120 subjects.

Diabetes research and clinical practice - 1 Aug 2017

Li Yan-Yan, Wang Hui, Yang Xin-Xing, Geng Hong-Yu, Gong Ge, Lu Xin-Zheng

Abstract excerpt

BACKGROUND: Aldose reductase (AR) gene C-106T polymorphism may be associated with diabetic nephropathy (DN) susceptibility, but the results of individual studies remain controversial. OBJECTIVE AND METHODS: To explore the relationship between AR gene C-106T gene polymorphism and DN in the Eastern Asians with type 2 diabetes mellitus (T2DM) population, we conducted a meta-analysis of 2120 participants from 5...

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PMID: 28651212
DOI: 10.1016/j.diabres.2017.06.014

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