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Article

Natural YMDD-motif mutants affect clinical course of lamivudine in chronic hepatitis B.

World journal of gastroenterology - 21 Feb 2015

Tan You-Wen, Ye Yun, Ge Guo-Hong, Zhao Wei, Gan Jian-He, Zhao Yun, Niu Zhi-Lin, Zhang Dong-Jun, Chen Li, Yu Xue-Jun, Yang Li-Jun

Abstract excerpt

AIM: To investigate the prevalence of nature tyrosine-methionine-aspartic acid-aspartic acid motif mutations in chronic hepatitis B (CHB) patients and to evaluate the efficacy of lamivudine. METHODS: A total of 1268 CHB patients were recruited from the outpatient and inpatient departments of six centers. Tyrosine-methionine-aspartic acid-aspartic acid (YMDD) mutations were analyzed using the hepatitis B virus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25717242
DOI: 10.3748/wjg.v21.i7.2089
PMCID: PMC4326144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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