Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

YMDD motif mutations in chronic hepatitis B antiviral treatment naïve patients: a multi-center study.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000

Tan You-Wen, Ge Guo-Hong, Zhao Wei, Gan Jian-He, Zhao Yun, Niu Zhi-Lin, Zhang Dong-Jun, Chen Li, Yu Xue-Jun, Yang Li-Jun

Abstract excerpt

OBJECTIVE: This study aimed to determine the natural prevalence of variants of tyrosine-methionine-aspartic acid-aspartic acid (YMDD) motif in patients with chronic hepatitis B (CHB), and to explore its relation with demographic and clinical features, hepatitis B virus (HBV) genotypes, and HBV DNA levels. METHODS: A total of 1,042 antiviral treatment naïve CHB patients (including with lamivudine [LAM]) in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Antiviral Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aspartic Acid

Share to DNA, Viral

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Methionine

Share to Tyrosine

Source

Identifiers

PMID: 22729192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

YMDD motif mutations in chronic hepatitis B antiviral treatment naïve patients: a multi-center study.PMID 22729192Read ↗

The naturally occurring YMDD mutation among patients chronically infected HBV and untreated with lamivudine: a systematic review and meta-analysis.Semantic proximity Read ↗

Natural YMDD-motif mutants affect clinical course of lamivudine in chronic hepatitis B.Semantic proximity Read ↗

Rate of YMDD motif mutants in lamivudine-untreated Iranian patients with chronic hepatitis B virus infection.Semantic proximity Read ↗

Prevelance of common YMDD motif mutations in long term treated chronic HBV infections in a Turkish population.Semantic proximity Read ↗

[Natural YMDD motif mutations of HBV polymerase in the chronic hepatitis B virus infected patients].Semantic proximity Read ↗

Correlation of the occurrence of YMDD mutations with HBV genotypes, HBV-DNA levels, and HBeAg status in Chinese patients with chronic hepatitis B during lamivudine treatment.Semantic proximity Read ↗

Clinical features of chronic hepatitis B patients with YMDD mutation after lamivudine therapy.Semantic proximity Read ↗

Hepatitis B virus (HBV) genotype and YMDD motif mutation profile among patients infected with HBV and untreated with lamivudine.Semantic proximity Read ↗

Interferon-α combined with lamivudine versus lamivudine monotherapy for the emergence of YMDD mutations in chronic hepatitis B infection: a meta-analysis of randomized controlled trials.Semantic proximity Read ↗

[YMDD motif variants detected by Inno-Lipa HBV DR assay in chronic hepatitis B patients during lamivudine therapy].Semantic proximity Read ↗

[A study on the mutation of P gene region including YMDD motif in hepatitis B virus].Semantic proximity Read ↗

YMDD motif variants in inactive hepatitis B carriers detected by Inno-Lipa HBV DR assay.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.