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Article

Alcohol-induced miR-27a regulates differentiation and M2 macrophage polarization of normal human monocytes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2015

Saha Banishree, Bruneau Johanna C, Kodys Karen, Szabo Gyongyi

Abstract excerpt

Alcohol abuse is a leading cause of liver disease characterized by liver inflammation, fatty liver, alcoholic hepatitis, or liver cirrhosis. Immunomodulatory effects of alcohol on monocytes and macrophages contribute to alcoholic liver disease. Alcohol use, an independent risk factor for progression of hepatitis C virus (HCV) infection-mediated liver disease, impairs host defense and alters cytokine production...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25716995
DOI: 10.4049/jimmunol.1402190
PMCID: PMC4517579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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